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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Biotherapy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Biotherapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский биотерапевтический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9784</issn><issn publication-format="electronic">1726-9792</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">863</article-id><article-id pub-id-type="doi">10.17650/1726-9784-2017-16-2-30-35</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Value of rationality cisplatin addition into prospidin hydrogel for intraperitoneal chemotherapy of Zajdel hepatoma</article-title><trans-title-group xml:lang="ru"><trans-title>Оценка целесообразности введения цисплатина в гидрогель с проспидином для внутрибрюшинной терапии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Reutovich</surname><given-names>M. Yu.</given-names></name><name xml:lang="ru"><surname>Ревтович</surname><given-names>М. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>mihail_revtovich@yahoo.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Istomin</surname><given-names>Yu. P.</given-names></name><name xml:lang="ru"><surname>Истомин</surname><given-names>Ю. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Krasko</surname><given-names>O. V.</given-names></name><name xml:lang="ru"><surname>Красько</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Treshalina</surname><given-names>H. M.</given-names></name><name xml:lang="ru"><surname>Трещалина</surname><given-names>Е. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shmak</surname><given-names>A. I.</given-names></name><name xml:lang="ru"><surname>Шмак</surname><given-names>А. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bychkovsky</surname><given-names>P. M.</given-names></name><name xml:lang="ru"><surname>Бычковский</surname><given-names>П. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff4"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yurkshtovich</surname><given-names>T. L.</given-names></name><name xml:lang="ru"><surname>Юркштович</surname><given-names>Т. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Golub</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Голуб</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Solomevich</surname><given-names>S. O.</given-names></name><name xml:lang="ru"><surname>Соломевич</surname><given-names>С. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff5"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rogov</surname><given-names>Y. I.</given-names></name><name xml:lang="ru"><surname>Рогов</surname><given-names>Ю. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff6"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Alexandrov National Cancer Center of Belarus</institution></aff><aff><institution xml:lang="ru">Республиканский научно-практический центр онкологии и медицинской радиологии им. Н.Н. Александрова</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">United Institute of Informatics Problems National Academy of Sciences of Belarus</institution></aff><aff><institution xml:lang="ru">Объединенный институт проблем информатики НАН Беларуси</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center</institution></aff><aff><institution xml:lang="ru">ФГБУ«РОНЦ им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Educational and Scientific Production Republican Unitary Enterprise «Unitehprom BSU»</institution></aff><aff><institution xml:lang="ru">Учебно-научно-производственное республиканское унитарное предприятие «Унитехпром БГУ»</institution></aff></aff-alternatives><aff-alternatives id="aff5"><aff><institution xml:lang="en">Research Institute for Physical Chemikal Problem of the Belarusian State University</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский институт физико-химических проблем Белорусского государственного университета</institution></aff></aff-alternatives><aff-alternatives id="aff6"><aff><institution xml:lang="en">Belarusian Medical Academy of Post-Graduate Education</institution></aff><aff><institution xml:lang="ru">ГУО «Белорусская медицинская академия последипломного образования»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-06-30" publication-format="electronic"><day>30</day><month>06</month><year>2017</year></pub-date><volume>16</volume><issue>2</issue><fpage>30</fpage><lpage>35</lpage><history><date date-type="received" iso-8601-date="2018-04-10"><day>10</day><month>04</month><year>2018</year></date></history><permissions/><self-uri xlink:href="https://bioterapevt.abvpress.ru/jour/article/view/863">https://bioterapevt.abvpress.ru/jour/article/view/863</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="ru"><kwd>гидрогелевая форма</kwd><kwd>цисплатин</kwd><kwd>проспидин</kwd><kwd>противоопухолевая активность</kwd><kwd>асцитная гепатома</kwd><kwd>prolonged hydrogel form</kwd><kwd>prospidin</kwd><kwd>cisplatin</kwd><kwd>antitumor activity</kwd><kwd>ascites hepatoma</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Wang Y., Gong Ch., Yang L. et al. 5-FU-hydrogel inhibits colorectal peritoneal carcinomatosis and tumor growth in mice. 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