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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Biotherapy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Biotherapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский биотерапевтический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9784</issn><issn publication-format="electronic">1726-9792</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">838</article-id><article-id pub-id-type="doi">10.17650/1726-9784-2016-15-4-53-58</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">DEVELOPMENT OF CYTOSTATIC EFFECT OF MONOCLONAL ANTIBODIES TO THE PROTEINS PRAME</article-title><trans-title-group xml:lang="ru"><trans-title>ПРОЯВЛЕНИЕ ЦИТОСТАТИЧЕСКОГО ЭФФЕКТА МОНОКЛОНАЛЬНЫХ АНТИТЕЛ К БЕЛКУ PRAME</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lyzhko</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Лыжко</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Misyurin</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Мисюрин</surname><given-names>Всеволод Андреевич</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>vsevolod.misyurin@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Finashutina</surname><given-names>Y. P.</given-names></name><name xml:lang="ru"><surname>Финашутина</surname><given-names>Ю. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Akhlynina</surname><given-names>T. V.</given-names></name><name xml:lang="ru"><surname>Ахлынина</surname><given-names>Т. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kesaeva</surname><given-names>L. A.</given-names></name><name xml:lang="ru"><surname>Кесаева</surname><given-names>Л. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tikhonova</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Тихонова</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kasatkina</surname><given-names>N. N.</given-names></name><name xml:lang="ru"><surname>Касаткина</surname><given-names>Н. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Solopova</surname><given-names>O. N.</given-names></name><name xml:lang="ru"><surname>Солопова</surname><given-names>О. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Baryshnikova</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Барышникова</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Misyurin</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Мисюрин</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Минздрава России</institution></aff><pub-date date-type="pub" iso-8601-date="2016-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2016</year></pub-date><volume>15</volume><issue>4</issue><fpage>53</fpage><lpage>58</lpage><history><date date-type="received" iso-8601-date="2018-04-10"><day>10</day><month>04</month><year>2018</year></date></history><permissions/><self-uri xlink:href="https://bioterapevt.abvpress.ru/jour/article/view/838">https://bioterapevt.abvpress.ru/jour/article/view/838</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="ru"><kwd>PRAME</kwd><kwd>моноклональные антитела</kwd><kwd>гибель клеток</kwd><kwd>PRAME</kwd><kwd>monoclonal antibodies</kwd><kwd>cell death</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Мисюрин В.А. Аутосомные раково-тестикулярные гены. 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