<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Biotherapy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Biotherapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский биотерапевтический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9784</issn><issn publication-format="electronic">1726-9792</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">825</article-id><article-id pub-id-type="doi">10.17650/1726-9784-2016-15-3-79-86</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">REFRACTORY FOLLICULAR LYMPHOMA AND SHORT-TERM PATIENTS SURVIVAL IN THE ERA OF TARGETED TREATMENT. WHAT IS THE REASON?</article-title><trans-title-group xml:lang="ru"><trans-title>РЕФРАКТЕРНОЕ ТЕЧЕНИЕ ФОЛЛИКУЛЯРНОЙ ЛИМФОМЫ И КОРОТКИЕ СРОКИ ЖИЗНИ БОЛЬНЫХ В ЭРУ ПРЕПАРАТОВ НАПРАВЛЕННОГО ДЕЙСТВИЯ. В ЧЕМ ПРИЧИНА?</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Falaleeva</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Фалалеева</surname><given-names>Наталья Александровна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>falaleeva-n@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff id="aff1"><institution>ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Минздрава России</institution></aff><pub-date date-type="pub" iso-8601-date="2016-09-30" publication-format="electronic"><day>30</day><month>09</month><year>2016</year></pub-date><volume>15</volume><issue>3</issue><fpage>79</fpage><lpage>86</lpage><history><date date-type="received" iso-8601-date="2018-04-10"><day>10</day><month>04</month><year>2018</year></date></history><permissions/><self-uri xlink:href="https://bioterapevt.abvpress.ru/jour/article/view/825">https://bioterapevt.abvpress.ru/jour/article/view/825</self-uri><abstract xml:lang="en"><p/></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="ru"><kwd>фолликулярная лимфома</kwd><kwd>прогноз</kwd><kwd>общий белок сыворотки крови</kwd><kwd>follicular lymphoma</kwd><kwd>prognosis</kwd><kwd>total serum protein level</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Casulo C., Byrtek M., Dawson K.L. et al. Early relapse of follicular lymphoma after rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone defines patients at high risk for death: an analysis from the National Lympho-Care Study. J Clin Oncol 2015; 33(23): 2516-22. DOI: 10.1200/JC0. 2014.59.7534. PMID: 26124482. PMCID: 26124482.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Zelenetz A.D., Abramson J.S., Advani R.H. et al. Non-Hodgkin’s lymphomas. J Natl Compr Canc Netw 2011; 9(5): 484 - 560. PMID: 21550968.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Liu Q., Fayad L., Cabanillas F. et al. Improvement of overall and failure-free survival in stage IV follicular lymphoma: 25 years of treatment experience at The University of Texas M. D Anderson Cancer Center. J Clin Oncol 2006; 24(10): 1582-9. DOI: 10.1200/JCO.2005.03.3696. PMID: 16575009.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Fisher R.I., LeBlanc M., Press O.W. et al. New treatment options have changed the survival of patients with follicular lymphoma. J Clin Oncol 2005; 23(33): 8447-52. DOI: 10.1200/JCO. 2005.03.1674. PMID: 16230674.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Swenson W.T., Wooldridge J.E., Lynch C.F. et al. Improved survival of follicular lymphoma patients in the United States. J Clin Oncol 2005; 23(22): 5019-26. DOI: 10.1200/JCO.2005.04.503. PMID: 15983392.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Press O.W., Unger J.M., Rimsza L.M. et al. Phase III randomized intergroup trial of CHOP plus rituximab compared with CHOP chemotherapy plus (131) iodine-tositumomab for previously untreated follicular non-Hodgkin lymphoma: SWOG S0016. J Clin Oncol 2013; 31(3): 314-20. DOI: 10.1200/JCO.2012.42.4101. PMID: 23233710. PMCID: PMC3732010.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Murakami S., Kato H., Higuchi Y et al. Prediction of high risk for death in patients with follicular lymphoma receiving rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone in first-line chemotherapy. J Ann Hematol 2016; 95(8): 1259-69. DOI: 10.1007/s00277-016-2690-2. PMID: 27220639.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Rummel M.J., Niederle N., Maschmeyer G. et al. Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre, randomised, phase 3 non-inferiority trial. Lancet 2013; 381(9873): 1203-10. DOI: 10.1016/S0140-6736(12)61763-2. PMID: 23433739.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Salles G., Seymour J.F., Offner F. et al. Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy(PRIMA): a phase 3, randomised controlled trial. Lancet 2011; 377(9759): 42-51. DOI: 10.1016/S0140-6736(10)62175-7. PMID: 21176949.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Solal-Celigny P., Roy P., Colombat P. et al. Follicular Lymphoma International Prognostic Index. J Blood 2004; 104(5): 1258-65. DOI: 10.1182/blood-2003-12-4434. PMID: 15126323.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Federico M., Bellei M., Marcheselli L. et al. Follicular Lymphoma International Prognostic Index 2: a new prognostic index for follicular lymphoma developed by the International Follicular Lymphoma Prognostic Factor Project. J Clin Oncology 2009; 27(27): 4555-62. DOI: 10.1200/JCO.2008.21.3991. PMID: 19652063.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>O’Shea D., O’Riain C., Taylor C. et al. The presence of TP53 mutation at diagnosis of follicular lymphoma identifies a high-risk group of patients with shortened time to disease progression and poorer overall survival. Blood 2008; 112(8): 3126-9. DOI: 10.1182/blood-2008-05-154013. PMID: 18628487. PMCID: PMC2954748.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Dave S.S., Wright G., Tan B. et al. Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med 2004; 351(21): 2159-69. DOI: 10.1056/NEJMoa041869. PMID: 15548776.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Andjelic B., Todorovic-Balint M., Antic D. et al. Follicular lymphoma patients with a high FLIPI score and a high tumor burden: a risk stratification model. Vojnosanit Pregl 2015; 72(1): 26-32. PMID: 26043587.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Prochazka V., Papajik T., Jarosova M. et al. Prognostic factors in follicular lymphoma in the rituximab era: how to identify a high-risk patient? Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2011; 155(2): 99-108. PMID: 21804618.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Swerdlow S.H., Campo E. Harris N.L. et al. (eds.) WHO classification of tumours of haematopoietic and lymphoid tissues. WHO Press 2008: 439.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Cheson B.D., Horning S.J., Coiffier B. et al. Report of an international workshop to standardize response criteria for non-Hodgkin’s lymphomas. NCI Sponsored International Working Group. J Clin Oncol 1999; 17(4): 1244. PMID: 10561185.</mixed-citation></ref></ref-list></back></article>
