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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Biotherapy</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Biotherapy</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский биотерапевтический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1726-9784</issn><issn publication-format="electronic">1726-9792</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1213</article-id><article-id pub-id-type="doi">10.17650/1726-9784-2020-19-3-12-20</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРЫ ЛИТЕРАТУРЫ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">PHYTOADAPTOGENS IN THE TUMOURS BIOTHERAPY AND GERIATRICS (PART 2)</article-title><trans-title-group xml:lang="ru"><trans-title>ФИТОАДАПТОГЕНЫ В БИОТЕРАПИИ ОПУХОЛЕЙ И ГЕРИАТРИИ (ЧАСТЬ 2)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6365-2888</contrib-id><name-alternatives><name xml:lang="en"><surname>Bocharova</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Бочарова</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="ru"><p>Ольга Алексеевна Бочарова</p></bio><email>imufarm@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4893-1472</contrib-id><name-alternatives><name xml:lang="en"><surname>Karpova</surname><given-names>R. V.</given-names></name><name xml:lang="ru"><surname>Карпова</surname><given-names>Р. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2342-9881</contrib-id><name-alternatives><name xml:lang="en"><surname>Bocharov</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Бочаров</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vershinskaya</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Вершинская</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Baryshnikova</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Барышникова</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kazeev</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Казеев</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5071-3581</contrib-id><name-alternatives><name xml:lang="en"><surname>Kucheryanu</surname><given-names>V. G.</given-names></name><name xml:lang="ru"><surname>Кучеряну</surname><given-names>В. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0132-167X</contrib-id><name-alternatives><name xml:lang="en"><surname>Kiselevskiy</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Киселевский</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исcледовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute of General Pathology and Pathophysiology</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Научно-исследовательский институт общей патологии и патофизиологии»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-10-13" publication-format="electronic"><day>13</day><month>10</month><year>2020</year></pub-date><volume>19</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>12</fpage><lpage>20</lpage><history><date date-type="received" iso-8601-date="2020-10-12"><day>12</day><month>10</month><year>2020</year></date><date date-type="accepted" iso-8601-date="2020-10-12"><day>12</day><month>10</month><year>2020</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://bioterapevt.abvpress.ru/jour/article/view/1213">https://bioterapevt.abvpress.ru/jour/article/view/1213</self-uri><abstract xml:lang="en"><p>Phytoadaptogens (ginseng, eleutherococcus, rhodiola rosea, aralia, etc.) have a wide spectrum of biological activity, supporting the body in a state of nonspecific increased resistance to stress. The second part of the review provides information of the phytoadaptogens normalizing effects on the cardiovascular system. Analyzes current data on the antitumor properties of phytoadaptogens in relation to the effect on the onset and development of tumours, metastasis, recurrence, development of cytostatic disease, confirming the prospect of their using in drugs for prevention and biotherapy of tumour diseases.</p><p>Past 1 see: Phytoadaptogens in the tumours biotherapy and geriatrics (Past 1). Russian Journal of Biotherapy 2020;19(2):13–21.</p></abstract><trans-abstract xml:lang="ru"><p>Фитоадаптогены (женьшень, элеутерококк, родиола розовая, аралия и др.) обладают широким спектром биологической активности, поддерживая организм в состоянии неспецифически повышенной сопротивляемости к стрессовым воздействиям. Во 2-й части обзора приводятся сведения о нормализующем влиянии фитоадаптогенов на сердечно-сосудистую систему. Проводится анализ современных данных о противоопухолевых свойствах фитоадаптогенов в отношении влияния на возникновение и развитие опухолей, метастазирование, рецидивирование, развитие цитостатической болезни, подтверждающий перспективу их использования в создании препаратов для профилактики и биотерапии опухолевых заболеваний.</p><p>Часть 1 см.: Фитоадаптогены в биотерапии опухолей и гериатрии (Часть 1). Российский биотерапевтический журнал 2020;19(2):13–21. Past 1 see: Phytoadaptogens in the tumours biotherapy and geriatrics (Past 1). Russian Journal of Biotherapy 2020;19(2):13–21.</p></trans-abstract><kwd-group xml:lang="en"><kwd>ADAPTOGENS</kwd><kwd>GINSENG</kwd><kwd>ELEUTHEROCOCCUS</kwd><kwd>PREVENTIVE ONCOLOGY</kwd><kwd>GEROPROTECTORS</kwd><kwd>IMMUNOMODULATORS</kwd><kwd>ANTITUMOUR THERAPY</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>АДАПТОГЕНЫ</kwd><kwd>ЖЕНЬШЕНЬ</kwd><kwd>ЭЛЕУТЕРОКОКК</kwd><kwd>ПРОФИЛАКТИЧЕСКАЯ ОНКОЛОГИЯ</kwd><kwd>ГЕРОПРОТЕКТОРЫ</kwd><kwd>ИММУНОМОДУЛЯТОРЫ</kwd><kwd>ПРОТИВООПУХОЛЕВАЯ ТЕРАПИЯ</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Gan X.T., Karmazyn M. Cardioprotection by ginseng: experimental and clinical evidence and underlying mechanisms. Can J Physiol Pharmacol 2018;96(9):859–68. DOI: 10.1139/cjpp-2018-0192.</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Bocharova O.A., Baryshnikov A.Yu., Davydov M.I. 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