Russian Journal of BiotherapyRussian Journal of BiotherapyРоссийский биотерапевтический журнал1726-97841726-9792Publishing House ABV Press113610.17650/1726-9784-2019-18-1-6-15REVIEWSОБЗОРЫ ЛИТЕРАТУРЫModern ideas about the origin, features of morphology, prognostic and predictive significance of tumor vesselsСовременные представления о происхождении, особенностях морфологии, прогностической и предиктивной значимости опухолевых сосудовhttps://orcid.org/0000-0001-8371-740XSenchukovaM. A.СеньчуковаМ. А.
Russian Federation

6 Sovetskaya St., Orenburg 460000;11 Gagarina Prospect, Orenburg 460021

460000 Оренбург, ул. Советская, 6;460021 Оренбург, пр-т Гагарина, 11

https://orcid.org/0000-0002-5796-3719MakarovaE. V.МакароваЕ. В.
Russian Federation

6 Sovetskaya St., Orenburg 460000;11 Gagarina Prospect, Orenburg 460021

460000 Оренбург, ул. Советская, 6;460021 Оренбург, пр-т Гагарина, 11

malena2419@yandex.ruKalininE. A.КалининЕ. А.
Russian Federation

11 Gagarina Prospect, Orenburg 460021

460021 Оренбург, пр-т Гагарина, 11

TkachevV. V.ТкачевВ. В.
Russian Federation

11 Gagarina Prospect, Orenburg 460021

460021 Оренбург, пр-т Гагарина, 11

Orenburg State Medical University of the Ministry of Health of the Russian FederationФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава РоссииOrenburg Regional Clinical Oncology DispensaryГБУЗ «Оренбургский областной клинический онкологический диспансер»Orenburg State Medical University of the Ministry of Health of the Russian FederationOrenburg Regional Clinical Oncology DispensaryФГБОУ ВО «Оренбургский государственный медицинский университет» Минздрава РоссииГБУЗ «Оренбургский областной клинический онкологический диспансер»Orenburg Regional Clinical Oncology DispensaryOrenburg Regional Clinical Oncology DispensaryГБУЗ «Оренбургский областной клинический онкологический диспансер»190420191816151904201919042019https://bioterapevt.abvpress.ru/jour/article/view/1136

The review presents modern ideas about the origin of tumor vessels and the features of their morphology. The various approaches to the classification of tumor vessel types and to the assessment of their clinical and prognostic significance are described. Also, the main problems associated with the use of angiogenesis blockers in the treatment of malignancies and their possible solutions are reflected in the review.

В обзоре изложены современные представления о происхождении опухолевых сосудов и особенностях их морфологии. Описаны различные подходы к классификации типов сосудов, оценке их клинической и прогностической значимости. Отражены основные проблемы, связанные с использованием блокаторов ангиогенеза при лечении злокачественных новообразований, и возможные пути их решения.

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