Relationships between classes of bioactive substances and medicinal properties of plants of the Abrau Peninsula: Mathematical approaches to assessment

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Abstract

Background. The work is devoted to the analysis of the pharmacological potential of the flora of the Abrau Peninsula based on data from scientific publications containing research results, indicating the relevant plants and the various biologically active substances they contain.

Aim. Choosing the optimal mathematical approach to assessing the relationship between the classes of substances that make up plants growing on the territory of the Abrau Peninsula and their medicinal properties.

Materials and methods. The relationship between the therapeutic properties of vascular plants and their chemical composition was investigated based on data collected from over 1 000 scientific publications. The analysis was performed using clustering methods and regression analysis.

Conclusion. The conducted research has made it possible to form a database of vascular plants with medicinal properties, identify patterns between medicinal properties and the chemical composition of plants, and predict promising plant species based on these patterns. The results obtained can be used for further research in the field of phytochemistry and pharmacology, as well as for the development of new medicines based on plants of the Abrau Peninsula.

About the authors

Ilya V. Markin

Innovative Technopolis “ERA”

Author for correspondence.
Email: era_otd6@mil.ru
ORCID iD: 0009-0006-2874-4177
Russian Federation, 41 Pionersky Ave., Anapa, Krasnodar Territory 353456

Nikita A. Galkin

Innovative Technopolis “ERA”

Email: era_otd6@mil.ru
ORCID iD: 0009-0001-0941-5021
Russian Federation, 41 Pionersky Ave., Anapa, Krasnodar Territory 353456

Marina A. Dzhavakhyan

All-Russian Scientific Research Institute of Medicinal and Aromatic Plants; K.M. Lakin Scientific and Educational Institute of Pharmacy, Russian University of Medicine, Ministry of Health of Russia

Email: era_otd6@mil.ru
ORCID iD: 0000-0003-2673-6203
Russian Federation, Build. 1, 7 Grina St., Moscow 117216; 7a Onezhskaya St., Moscow 125438

Elena S. Shchelkanova

Innovative Technopolis “ERA”

Email: era_otd6@mil.ru
ORCID iD: 0000-0003-0672-8820
Russian Federation, 41 Pionersky Ave., Anapa, Krasnodar Territory 353456

Nikolay B. Fadeev

All-Russian Scientific Research Institute of Medicinal and Aromatic Plants

Email: era_otd6@mil.ru
ORCID iD: 0000-0003-2658-6348
Scopus Author ID: era_otd6@mil.ru
Russian Federation, Build. 1, 7 Grina St., Moscow 117216

Natalya V. Varlamova

Innovative Technopolis “ERA”

Email: era_otd6@mil.ru
ORCID iD: 0000-0002-6100-2427
Russian Federation, 41 Pionersky Ave., Anapa, Krasnodar Territory 353456

Artur S. Baimashev

Innovative Technopolis “ERA”; N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Email: era_otd6@mil.ru
ORCID iD: 0000-0002-0299-7794
Russian Federation, 41 Pionersky Ave., Anapa, Krasnodar Territory 353456; 24 Kashirskoe Shosse, Moscow, 115522

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