MODIFICATION OF ADDITIVE TECHNOLOGIES FOR OBTAINING MEDICAL FORMS

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Abstract

This review presents technological approaches to 4-D printing, which are modifications of additive technologies. Showing the distinctive features of this technology from the three-dimensional printing. The use of four-dimensional printing in pharmaceutical technology and advantages over traditional methods of creating dosage forms are described. Demonstrated classification of adaptive materials, the principles of their application and features of printing equipment. Examples of adaptive materials are presented, including smart polymers and stimuli sensitive hydrogels. The advantages of this type of production, its development prospects and technological features of the production of microcapsules, hydrogels and mucoadhesive films of smart polymers by additive printing technology are given.

About the authors

K. V. Alekseev

Research Zakusov Institute of Pharmacology;
“Reaviz” Medical University

Russian Federation

E. V. Blynskaya

Research Zakusov Institute of Pharmacology

Russian Federation

S. V. Tishkov

Research Zakusov Institute of Pharmacology

Author for correspondence.
Email: sergey-tishkov@ya.ru
ORCID iD: 0000-0002-8321-6952
Сергей Валерьевич Тишков Russian Federation

V. K. Alekseev

Research Zakusov Institute of Pharmacology

Russian Federation

A. A. Ivanov

Research Zakusov Institute of Pharmacology

Russian Federation

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