Modern ideas about the origin, features of morphology, prognostic and predictive significance of tumor vessels

M. A. Senchukova; Сеньчукова М. А.; E. V. Makarova; Макарова Е. В.; E. A. Kalinin; Калинин Е. А.; V. V. Tkachev; Ткачев В. В.

doi:10.17650/1726-9784-2019-18-1-6-15

Modern ideas about the origin, features of morphology, prognostic and predictive significance of tumor vessels

Authors: Senchukova M.A.¹^,2, Makarova E.V.¹^,2, Kalinin E.A.², Tkachev V.V.²
Affiliations:
1. Orenburg State Medical University of the Ministry of Health of the Russian Federation
2. Orenburg Regional Clinical Oncology Dispensary
Issue: Vol 18, No 1 (2019)
Pages: 6-15
Section: REVIEWS
Published: 19.04.2019
URL: https://bioterapevt.abvpress.ru/jour/article/view/1136
DOI: https://doi.org/10.17650/1726-9784-2019-18-1-6-15
ID: 1136

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Abstract

The review presents modern ideas about the origin of tumor vessels and the features of their morphology. The various approaches to the classification of tumor vessel types and to the assessment of their clinical and prognostic significance are described. Also, the main problems associated with the use of angiogenesis blockers in the treatment of malignancies and their possible solutions are reflected in the review.

Keywords

tumor angiogenesis, tumor microvessels, angiogenesis blockers

About the authors

M. A. Senchukova

Orenburg State Medical University of the Ministry of Health of the Russian Federation;
Orenburg Regional Clinical Oncology Dispensary

ORCID iD: 0000-0001-8371-740X

6 Sovetskaya St., Orenburg 460000;
11 Gagarina Prospect, Orenburg 460021

Russian Federation

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