Biomarkers of renal cell carcinoma


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Abstract

Renal cell carcinoma (RCC) ranks first in mortality among urogenital tumors and is the most common disease after prostate and bladder cancer. Early detection of RCC allows immediately undertaking appropriate treatment, which significantly increases the survival of patients. In the case of the asymptomatic RCC, timely diagnosis in the early stages is usually difficult. To date, the problem of searching for molecular markers of clear cell RCC, which allows to determine the stage, metastatic potential and prognosis of disease, or select a treatment regimen remains topical. Of particular interest are early-stage biomarkers of RCC and its metastatic potential, as well as markers that can be obtained by non-invasive or minimally invasive methods. This review presents modern methods for diagnosing RCC using biomarkers.

About the authors

S. A. Aschuba

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

Author for correspondence.
Email: Zanda82@mail.ru
24 Kashirskoe Shosse, Moscow 115478 Russian Federation

E. S. Solomko

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

24 Kashirskoe Shosse, Moscow 115478 Russian Federation

D. A. Khochenkov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

ORCID iD: 0000-0002-5694-3492
24 Kashirskoe Shosse, Moscow 115478 Russian Federation

A. A. Osipova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

24 Kashirskoe Shosse, Moscow 115478 Russian Federation

E. V. Stepanova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia

24 Kashirskoe Shosse, Moscow 115478 Russian Federation

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