Email this article Possibilities of application of genetic and serum oncomarkers in early diagnostics of breast cancer
- Authors: Ryabchikov D.A.1, Dudina I.A.2, Vorotnikov I.K.1, Denchik D.A.1, Shusharin A.S.1, Abdullaeva E.I.2
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Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
- Sechenov University
- Issue: Vol 17, No 1 (2018)
- Pages: 14-22
- Section: REVIEWS
- Published: 27.02.2018
- URL: https://bioterapevt.abvpress.ru/jour/article/view/1108
- DOI: https://doi.org/10.17650/1726-9784-2018-17-1-14-22
- ID: 1108
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Abstract
Currently, mammography is the main screening method for diagnosing breast cancer (BC); but the process of carcinogenesis begins long before the appearance of a visualized tumor. For successful early diagnosis of breast cancer, a systematic approach is required, that includes all stages of tumor development. On the example of BC we consider the possibilities of integrating the recent scientific achievements of oncogenetics and proteomics with standard methods. In this article we investigate the possibilities of using genetic research, serum cancer markers and radiation methods for early diagnosis of BC. This article also presents potential options for managing high-risk development of this disease.
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About the authors
D. A. Ryabchikov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Author for correspondence.
Email: dr.denisr@mail.ru
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
I. A. Dudina
Sechenov UniversityBldg. 2, 8 Trubetskaya St., Moscow 119991 Russian Federation
I. K. Vorotnikov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia24 Kashirskoe Shosse, Moscow 115478 Russian Federation
D. A. Denchik
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia24 Kashirskoe Shosse, Moscow 115478 Russian Federation
A. S. Shusharin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia24 Kashirskoe Shosse, Moscow 115478 Russian Federation
E. I. Abdullaeva
Sechenov UniversityBldg. 2, 8 Trubetskaya St., Moscow 119991 Russian Federation
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